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Events
2002-2003
Wednesday, March 26th, 2003 Imagine the impact of being able to predict Dr. Pat Costigan will present his ideas for future research
on Background to this The gait lab here at Queen's has been in place for more than 12 years with our first subject tested in January 1990. Since then we have developed processing and analysis procedures that have turned out to be sensitive to changes in gait mechanics between groups. We can clearly distinguish between normal volunteers and other populations, such as those with knee osteoarthritis (OA) or between young and elderly. Recent work has shown that we can predict pre-operatively which patients will receive a hemi and which will receive a total knee implants. Work on a group of normal volunteers, followed over 5 to 10 years, suggests that gait measure may be able to predict those at risk for the development of knee OA. These very exciting results suggest that we can use gait analysis to predict, follow and perhaps intervene in the development of OA. The question is where to go from here. At present there is little we can do to help those with OA and are more interested in working with those at risk of developing OA. But who are these people? Who will progress? What mechanical factors precipitate progression? Can we alter those mechanical factors? Can we slow progression? Why we would like you to attend This BIG SCIENCE meeting will focus on generating ideas and collaborations. We hope you will attend because we believe solutions will be found by bringing the strengths of many disciplines. About the speaker Dr. Pat Costigan graduated from the University of New Brunswick with a BSc. in Sports Science in 1980. He came to Queen's to study under Dr. Gavin Reid in the School of Physical and Health Education. After graduating with an MSc. and specializing in biomechanics. Dr. Costigan worked in several departments at Queen's including Physical and Health Education and Mechanical Engineering and the School of Rehabilitation Therapy. For the most part, this work involved developing gait analysis systems. In 1993 he was the second applicant to the new PhD. program in Physical and Health Education again working under Dr. Reid. After graduating he was offered a faculty position within the department. Wednesday, February 26th, 2003 Workshop - Strategic Development for HMRC The goal of this workshop will be to pool our research ideas in order to craft a vision for how HMRC will move forward over the next five years as a cohesive, multidisciplinary group. Wednesday, January 29th, 2003 Dr. Inka Brockhausen and Dr. Mark Harrison
BIG SCIENCE MEETING Degradation products of structural proteins of connective tissue have a long history as stimulatory growth factor since Urist's pioneering experiments on bone morphogenic proteins. Currently we are collaborating with Millennium Biologix Inc. on a research project, which is examining the effect of a novel class of bone and cartilage stimulating peptides. These growth factors are small peptides which can be directly synthesized and offer several advantages over bone morphogenic proteins. The molecular action of these bone cartilage-stimulating peptides (BCSP) is unknown. However, we hae shown that BCSP alter cell growth and glycosylation. The goal of this "Big Science" meeting is to invite additional collaborators to join our research team. This will allow for further investigation into a number of different lines of research. In particular, we are interested in identifying the molecular mechanisms for this novel class of peptides. In addition we wish to utilize these peptides in animal models for osteoporosis, cartilage and bone injury and repair.
Dr. Inka Brockhausen, Associate Professor, Department of Medicine and Department of Biochemistry Dr. Mark Harrision, Orthopaedic Surgeon Wednesday, November 27,2002 Is it possible through in vivo measurements of bone architecture and density to predict fracture risk in patients? will present his ideas for future research directions on a finite element model to predict risk of fracture. Finite element method (FEM) model to predict fracture risk based on in vivo images of bone architecture and
mineral density. About the speaker:
Wednesday, October 23, 2002 The response of tissue to
mechanical loading underlies a number of processes including remodelling of
bone, soft tissue healing, cartilage growth and cartilage degeneration.
Currently, a large number of studies are addressing the so-called concept of
mechano-transduction - how cells sense and respond to mechanical stimuli such as
stress or strain state. However, there are no clear models that link the
mechanical, biochemical, and biological pathways that have been observed. This
knowledge could identify strategies to solve currently intractable problems such
as: providing engineered soft tissue of sufficient strength to be useful,
identifying methods of mitigating cartilage damage in osteoarthritis, and
developing strategies to limit bone strength loss due to
osteoporosis. Wednesday, September 25, 2002 Obesity represents a significant risk factor for the develoment of knee arthritis in patients
undergoing surgery, as well as for various co-morbidities that affect their quality of life and create pressure on the health system.
The perception of orthopaedic surgeons is that obesity increases the risk of complications and has negative impact on the beneficial effects of surgery.
Despite being informed of their increased risks and told to lose weight before surgery, patients rarely do so. Powerpoint presentation by Dr. Harrison For further information please contact: Human Mobility Research Centre Angada 1 Syl and Molly Apps Research Centre Kingston General Hospital Kingston, Ontario K7L 2V7 Telephone (613) 548-2430 Fax (613) 549-2529 hmrc@post.queensu.ca | ||||||
    
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